Re: [asa] writing DNA...

From: David Campbell <>
Date: Mon Sep 29 2008 - 18:26:49 EDT

> This actually has made me think of a question that I hadn't considered
> before. Are there short sequences that statistically should occur in
> proteins, but don't because their structure would be so inimical to all
> protein functions that they would be universally strongly selected against?
> I doubt that any short sequence could have that strong an effect, but it
> would be interesting if there were any such sequences.

Probably long strings of a single amino acid are disproportionally
rare, especially cysteine with its special structutal function.

A search of the entire database would indeed make it likely to find
sequences up to about 10 letters or so. However, I could make more of
a case for specified complexity in the GAINFIST-cox1 example, because
that's in a single stretch of less than 300 amino acids which is the
only protein sequence known for a lot of the mussels. On the other
hand, I didn't know in advance to look for the phrase, but then there
wasn't any a priori reason for ID folks to get excited about flagella,

Dr. David Campbell
425 Scientific Collections
University of Alabama
"I think of my happy condition, surrounded by acres of clams"
To unsubscribe, send a message to with
"unsubscribe asa" (no quotes) as the body of the message.
Received on Mon Sep 29 18:27:40 2008

This archive was generated by hypermail 2.1.8 : Mon Sep 29 2008 - 18:27:41 EDT