Date: Thu May 29 2003 - 21:38:40 EDT
I'd like to thank Terry for forwarding my emails to this list. I will
probably subscribe to the list after my email address "stabilizes"
(Comcast bought ATT Broadband's internet service: My address will have
to change yet again).
Jim Armstrong asked about pseudogenes and functionality...
It's probably fair to say that most people think most pseudogenes
probably don't have a specific or "realized" purpose. Many pseudogenes
exist as defective copies of existing, functional genes. In the case
of "processed pseudogenes", many were probably "broken" in some way from
the moment they were made. Below is a link to Mark Gerstein's lab pages
And a recent paper out of his group:
Harrison PM, Gerstein M., Studying genomes through the aeons: protein
families, pseudogenes and proteome evolution. (J Mol Biol 2002 May
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