All the data in physics can be collected by detectors which interact with
the system observed via the basic interactions in nature (gravitational,
nuclear and weak/electromagnetic).
We do not need humans to collect the data--of course, humans are needed to
set up the experiments. Therefore, such mere experimental data, by the
nature of the detectors, can never say anything about God the Creator.
However, the human mind does come into play when it comes to making up a
theory to explain the data. Also, the human being is the "detector" of the
spiritual realm and it is in this manner that the issue of God being behind
the Creation comes into the picture.
I am sure that what is true in physics typifies what is true in any other
science. It is then obvious why in scientific theories there is no need of
God as, I believe, Descartes said. However, in the description of the
totality of the human experience, one cannot do without God the Creator.
The Greeks (Plato or Aristotle) told us to "know thyself" but did not give a
prescription on how to do that. I say that to know thyself you must not only
know God but also know His Son Jesus Christ.